How do I check to see if I am resistant to the aspirin I am taking?
There is a test called "AspirinWorks" that measures thomboxane in your urine. Your doctor can order this simple urine test through SED Medical Laboratories.

What if my doctor tells me that I am resistant to the aspirin I am taking?
Your doctor can increase the dose of aspirin you are taking or put you on another form of platelet therapy.

Aspirinworks.com

Healthcare Provider Information

New: Recent scientific evidence supporting the need to check for aspirin resistance

Why would my patient not respond to Aspirin Therapy?
There may be several reasons a patient is not responding as expected. 

• Aspirin dosage may be incorrect for the patient.
• Cholesterol levels over 220 mg/dl.
• Non-steroidal anti-inflammatory compounds taken prior or together with aspirin.
• There may be genetic factors- negative Pla2
• Other pathways of platelet activation exist that are not blocked by aspirin.

How is resistance determined?
An immunoassay test measures levels of urinary 11-dehydrothromboxane B2.  Levels of this metabolite, the result of in-vivo platelet activation, are reduced in proportion to aspirin's effectiveness.

How do I order AspirinWorks for my patient?

• Providers already established with SED can simply call for ordering details and specimen preparation.
• New providers need to call for account set up, details and requisition ordering.

S.E.D. Marketing Department

505-727-6363

1-800-999-LABS ext 6232

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